Andre E Nel Selected Research

Enzymes

1/2015	Use of a lipid-coated mesoporous silica nanoparticle platform for synergistic gemcitabine and paclitaxel delivery to human pancreatic cancer in mice.
1/2013	Nrf2 deficiency in dendritic cells enhances the adjuvant effect of ambient ultrafine particles on allergic sensitization.
9/2005	The role of phase II antioxidant enzymes in protecting memory T cells from spontaneous apoptosis in young and old mice.
9/2004	Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals.

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Andre E Nel Research Topics

Disease

19	Neoplasms (Cancer) 02/2024 - 05/2007
14	Pancreatic Neoplasms (Pancreatic Cancer) 02/2024 - 10/2009
14	Inflammation (Inflammations) 01/2021 - 03/2002
13	Asthma (Bronchial Asthma) 01/2019 - 12/2003
5	Adenocarcinoma 01/2022 - 01/2015
3	Anaphylaxis (Anaphylactic Shock) 01/2023 - 01/2021
3	Breast Neoplasms (Breast Cancer) 06/2021 - 02/2013
3	Colonic Neoplasms (Colon Cancer) 01/2021 - 01/2019
3	Pneumonia (Pneumonitis) 01/2018 - 05/2012
2	Mesothelioma 11/2023 - 01/2023
2	Hypersensitivity (Allergy) 01/2023 - 05/2007
2	Neoplasm Metastasis (Metastasis) 11/2018 - 05/2017
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 05/2011 - 09/2010
2	Atherosclerosis 09/2009 - 03/2008
2	Lung Diseases (Lung Disease) 05/2008 - 01/2007
1	Hypothermia 02/2022
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Eosinophilia 01/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2019

Drug/Important Bio-Agent (IBA)

12	Particulate MatterIBA 01/2013 - 03/2002
10	Silicon Dioxide (Silica)FDA LinkGeneric 03/2021 - 05/2007
6	CytokinesIBA 01/2023 - 09/2008
6	AllergensIBA 01/2023 - 04/2006
6	AntioxidantsIBA 01/2013 - 03/2002
5	Proteins (Proteins, Gene)FDA Link 02/2022 - 01/2005
5	Irinotecan (Camptosar)FDA LinkGeneric 01/2022 - 02/2016
5	Paclitaxel (Taxol)FDA LinkGeneric 05/2017 - 05/2007
4	PerforinIBA 01/2021 - 11/2018
4	AntigensIBA 01/2021 - 05/2007
4	Liposomes (Liposome)IBA 10/2020 - 11/2013
4	LipidsIBA 02/2016 - 09/2009
4	EnzymesIBA 01/2015 - 09/2004
4	Environmental Pollutants (Pollutants, Environmental)IBA 03/2008 - 12/2003
3	Gemcitabine FDA Link 01/2016 - 11/2013
3	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2013 - 08/2010
3	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2012 - 12/2003
3	Air Pollutants (Pollutants, Air)IBA 09/2009 - 06/2005
3	Oxidants (Oxidizing Agents)IBA 10/2008 - 08/2006
3	Glutathione (Reduced Glutathione)IBA 05/2008 - 09/2005
2	EpitopesIBA 01/2023 - 01/2021
2	Immunoglobulin E (IgE)IBA 01/2023 - 01/2019
2	Polylactic Acid-Polyglycolic Acid CopolymerIBA 02/2022 - 01/2021
2	Lipid Bilayers (Lipid Bilayer)IBA 03/2021 - 05/2017
2	CalreticulinIBA 03/2021 - 01/2021
2	Blocking AntibodiesIBA 01/2021 - 11/2018
2	Granzymes (Granzyme)IBA 01/2021 - 10/2020
2	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 10/2020 - 11/2018
2	Peptides (Polypeptides)IBA 01/2019 - 05/2017
2	Neuropilin-1IBA 05/2017 - 01/2017
2	Small Interfering RNA (siRNA)IBA 02/2013 - 08/2010
2	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 02/2013 - 05/2011
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 02/2013 - 08/2010
2	PolyethyleneimineIBA 02/2013 - 05/2011
2	1-(2-(dodecyloxy)ethyl)pyrrolidine hydrochloride (DEP)IBA 08/2006 - 06/2005
2	Vehicle Emissions (Emissions, Vehicle)IBA 06/2005 - 12/2003
1	nintedanibIBA 02/2024
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2024
1	AsbestosIBA 11/2023
1	Lipid NanoparticlesIBA 01/2023
1	Interleukin-10 (Interleukin 10)IBA 01/2023
1	Messenger RNA (mRNA)IBA 01/2023
1	MineralsIBA 01/2023
1	taconiteIBA 01/2023
1	hypoxanthine arabinoside (ara-H)IBA 02/2022
1	Peptide Hydrolases (Proteases)FDA Link 02/2022
1	Polyglactin 910IBA 02/2022
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 02/2022
1	Toll-Like Receptor AgonistsIBA 01/2022
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2022
1	HMGB1 Protein (HMG1)IBA 03/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021
1	Immunomodulating AgentsIBA 01/2021
1	PlatinumIBA 01/2021
1	CurcuminIBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	2- hydroxy- 3- (5- ((morpholin- 4- yl)methyl)pyridin- 2- yl)- 1H- indole- 5- carbonitrileIBA 01/2021
1	Mitoxantrone (Novantrone)FDA LinkGeneric 10/2020
1	1-methyltryptophanIBA 10/2020
1	HMGB ProteinsIBA 10/2020
1	ProdrugsIBA 10/2020
1	Apolipoproteins B (ApoB)IBA 01/2019
1	Fossil Fuels (Fossil Fuel)IBA 01/2019
1	LigandsIBA 01/2019
1	Drug CombinationsIBA 11/2018
1	N-end cysteine peptide tumor-homing peptideIBA 01/2017
1	Complement System Proteins (Complement)IBA 01/2017
1	Membrane LipidsIBA 01/2015
1	DNA (Deoxyribonucleic Acid)IBA 01/2015
1	Albumin-Bound Paclitaxel FDA Link 01/2015
1	Cytidine DeaminaseIBA 01/2015
1	Transcription Factors (Transcription Factor)IBA 01/2013
1	MetalsIBA 05/2012
1	cobalt tetraoxideIBA 05/2012
1	carboxyl radical (COO-)IBA 05/2012

Therapy/Procedure

10	Immunotherapy 11/2023 - 11/2017
5	Drug Therapy (Chemotherapy) 01/2021 - 05/2017
4	Therapeutics 03/2021 - 05/2007
4	Intravenous Injections 01/2021 - 05/2011
2	Nanospheres 01/2008 - 08/2006